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Invitrogen
Complement Factor B Monoclonal Antibody (9B8)
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产品信息
HYB 008-02-02
产品规格
宿主/亚型
Mouse
/ IgG1, kappa
分类
Monoclonal
类型
Antibody
克隆号
9B8
抗原
Factor B isolated from human plasma.
偶联物
形式
Liquid
浓度
0.98 mg/mL
规格
196 µg
保存条件
4°C, store in dark
运输条件
Wet ice
RRID
产品详细信息
HYB 008-02-02 is specific for the Bb fragment of human factor B. Antibody binding abolishes the formation of C3bBb complexes.
HYB 008-02-02 has been successfully used in ELISA and Western blotting procedures. HYB 008-02-02 reacts strongly with factor B. Strong reaction is seen in sandwich ELISA in combination with a polyclonal antibody against factor B (e.g. DAKO A 343). In Western blotting after SDS-PAGE, HYB 008-02-02 reacts with the Bb fragment of factor B in non-reduced form only. After coupling to an activated CNBr-sepharose column, HYB 008-02-02 is suitable for affinity purification of human factor B.
The HYB 008-02-02 immunogen complement factor B isolated from human plasma.
Epitope specificity differs from that of HYB 008-06-02. Epitope specificity differs from that of HYB 008-04-02 and HAV 005-02-02 but slightly overlap as determined by inhibition ELISA.
NOTE: Concentration is lot-dependent and can vary from 0.85-1.15 mg/mL
靶标信息
Factor B is a component of the alternative complement pathway. The protein is a single chain polypeptide with a molecular mass of 93 kDa. Factor B is cleaved by factor D into the Ba component (30 kDa) and the Bb (63 kDa). Bb together with C3b forms the alternative pathway C3 convertase C3bBb.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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